6
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T83019 | Antiproliferative agent-38 | ||
Antiproliferative Agent-38 (COM 18), a tetracyclic compound, features a reactive ring nitrogen (likely the quinoline moiety) that resists N-alkylation. Despite its classification, it neither exhibits anti-malarial proper... | |||
T78381 | (R)-Necrocide 1 | Others | |
(R)-Necrocide 1 (compound (R)-38) is a potent anticancer agent with antiproliferative activity [1]. | |||
T61616 | Antitumor agent-38 | ||
Antitumor agent-38 is a highly effective antitumor compound that exhibits antiproliferative activity towards cancer cells. It induces cell cycle arrest specifically at the late S and G2/M phase, while not impeding microt... | |||
T78051 | Necrocide 1 | Others | |
Necrocide 1 (compound (S)-38), a potent anticancer agent, exhibits antiproliferative activity with IC50 values of 0.48 nM for MCF-7 and 2 nM for PC3 cancer cell lines, respectively [1]. | |||
T78773 | Tubulin inhibitor 38 | ||
Tubulin Inhibitor 38 (Compound 14), a tetrazole-based agent, demonstrates significant antiproliferative effects by inducing mitotic arrest and blocking the cell cycle at the G2/M phase, ultimately triggering apoptosis. A... | |||
T83951 | TM2 TEAD inhibitor | ||
TM2 TEAD inhibitor, a robust and reversible inhibitor of the TEA domain transcription factor, presents dual inhibitory concentrations (IC50) of 38 nM for TEAD4 auto-palmitoylation and 156 nM for TEAD2 palmitoylation. It ... |